Semax — Synthetic Heptapeptide Research Compound
Catalog ID: SEMX | CAS: 80714-61-0 | Sequence: Met-Glu-His-Phe-Pro-Gly-Pro
Compound Overview
Semax is a synthetic ACTH₄₋₁₀ analog developed as a research peptide to explore mechanisms of neuromodulation, neuroprotection, and peptide-mediated gene expression.
It is studied for its influence on brain-derived neurotrophic factor (BDNF) and corticotropin receptor pathways in laboratory settings.
Not for human consumption or therapeutic application.
Molecular Characteristics
- Synonyms: ACTH₄₋₁₀ analog; Heptapeptide neuromodulator
- CAS Number: 80714-61-0
- Sequence: Met-Glu-His-Phe-Pro-Gly-Pro
- Molecular Formula: C37H51N9O10S
- Molecular Weight: ≈ 753.9 g/mol
- Purity: ≥ 98% (HPLC)
- Formulation: Lyophilized peptide powder
Physical Properties
- Appearance: White to off-white lyophilized powder
- Solubility: Sterile water or 0.6 % acetic acid (for research use only)
- Container: Sterile sealed vial
Storage & Stability
- Unreconstituted: Store at −20 °C, protected from light and moisture.
- Reconstituted: Aliquot and store at −20 °C; avoid repeated freeze–thaw cycles.
Research Context
Semax is used in in vitro and in vivo model systems investigating corticotropin signaling, synaptic plasticity, and peptide-induced gene expression.
Studies focus on its role as a neuromodulatory peptide analog that interacts with melanocortin receptors and contributes to neuronal adaptation under oxidative or metabolic stress.
For laboratory research use only. Not for human use, ingestion, or therapeutic/diagnostic applications.
Buyer assumes all responsibility for safe handling in accordance with institutional and federal safety standards.
