NAD⁺ — Nicotinamide Adenine Dinucleotide Research Compound

Catalog ID: NAD | CAS: 53-84-9 | Molecular Formula: C₂₁H₂₇N₇O₁₄P₂

Compound Overview

Nicotinamide Adenine Dinucleotide (NAD⁺) is a naturally occurring redox coenzyme involved in fundamental metabolic reactions within all living cells.
In laboratory research, NAD⁺ is studied for its role in electron transport, mitochondrial energy conversion, and sirtuin enzyme activation pathways.
For research use only — not for human consumption or therapeutic application.

Molecular Characteristics

• Synonyms: β-Nicotinamide Adenine Dinucleotide; Diphosphopyridine Nucleotide
• CAS Number: 53-84-9
• Structure Type: Redox coenzyme (oxidized form)
• Molecular Formula: C₂₁H₂₇N₇O₁₄P₂
• Molecular Weight: ≈ 663.4 g/mol
• Purity: ≥ 98 % (HPLC verified)
• Formulation: Lyophilized crystalline powder

Physical Properties

• Appearance: White to pale yellow crystalline powder
• Solubility: Water-soluble; use sterile water or PBS buffer for laboratory preparation
• Container: Sterile sealed vial

Storage & Stability

• Unreconstituted: Store at −20 °C, protected from light and moisture.
• Reconstituted: Store aliquots at −20 °C; avoid repeated freeze–thaw cycles.

Research Context

NAD⁺ plays a key role in research examining mitochondrial bioenergetics, oxidative phosphorylation, and redox homeostasis.
It serves as a cofactor in numerous enzymatic systems, including sirtuins (SIRT1–7), PARP enzymes, and dehydrogenase complexes.
Studies often focus on its importance in cellular metabolism, aging models, and mitochondrial communication.