Cagrilintide — Long-Acting Amylin Analog Research Compound

Catalog ID: CAGR | CAS: 1338225-97-0 | Molecular Formula: C₁₇₈H₂₈₂N₅₀O₅₁S | Molecular Weight: ≈ 3972.5 g/mol

Compound Overview

Cagrilintide is a synthetic, long-acting amylin analog peptide engineered for enhanced molecular stability and sustained receptor engagement.
It is studied in controlled laboratory environments for its effects on amylin and calcitonin receptor binding, peptide signal transduction, and metabolic regulation.
This compound provides a valuable research model for exploring energy homeostasis and peptide pharmacokinetics.
For laboratory research use only — not for human consumption or therapeutic application.

Molecular Characteristics

• Synonyms: AM833; Cagrilintide acetate; Amylin analog
• CAS Number: 1338225-97-0
• Molecular Formula: C₁₇₈H₂₈₂N₅₀O₅₁S
• Molecular Weight: ≈ 3972.5 g/mol
• Purity: ≥ 98% (HPLC verified)
• Formulation: Lyophilized peptide powder

Physical Properties

• Appearance: White to off-white lyophilized powder
• Solubility: Sterile water or 0.6% acetic acid (for research use only)
• Container: Sterile sealed vial

Storage & Stability

• Unreconstituted: Store at −20 °C, protected from light and moisture.
• Reconstituted: Aliquot and store at −20 °C; avoid repeated freeze–thaw cycles.

Research Context

Cagrilintide is utilized in in vitro and in vivo research to investigate amylin receptor activity, peptide stability, and metabolic peptide mechanisms.
Its amylin-mimetic structure enables examination of calcitonin receptor complexes, GPCR signaling dynamics, and ligand-receptor kinetics.
Research applications include studies on energy regulation, signal amplification, and structure–activity relationships within the amylin family of peptides.