VIP — Vasoactive Intestinal Peptide

Catalog ID: VIP | CAS: 40077-57-4 | Sequence: HSDAVFTDNYTRLRKQMAVKKYLNSILN

Compound Overview

Vasoactive Intestinal Peptide (VIP) is a naturally occurring neuropeptide consisting of 28 amino acids.
It is provided in research-grade purity for the investigation of cellular signaling, smooth-muscle relaxation, and immune-modulatory mechanisms in controlled laboratory environments.
Not for human consumption or therapeutic application.

Molecular Characteristics

• Synonyms: Vasoactive Intestinal Polypeptide; VIP (human)
• Sequence: HSDAVFTDNYTRLRKQMAVKKYLNSILN
• Molecular Formula: C₁₄₇H₂₃₇N₄₃O₄₃S
• Molecular Weight: ~3326.8 g/mol
• Formulation: Lyophilized peptide powder
• Purity: ≥ 98% (HPLC verified)

Physical Properties

• Appearance: White to off-white lyophilized powder
• Solubility: Sterile water or phosphate buffer (laboratory preparation only)
• Container: Sterile 5 mg vial

Storage & Stability

• Unreconstituted: Store at −20 °C protected from light and moisture.
• Reconstituted: Aliquot and store at −20 °C. Avoid repeated freeze–thaw cycles.

Research Context

VIP has been utilized in in vitro and in vivo research to examine its role in cyclic AMP signaling, vasodilatory pathways,
neuroprotection, and cytokine modulation.
Ongoing investigations focus on its molecular influence within the autonomic, immune, and respiratory systems of model organisms.