Glutathione (GSH) — Tripeptide Antioxidant Research Compound

Catalog ID: GLUT | CAS: 70-18-8 | Sequence: γ-L-Glutamyl-L-Cysteinyl-Glycine

Compound Overview

Glutathione (GSH) is a tripeptide composed of glutamic acid, cysteine, and glycine, forming one of the most important intracellular reducing agents in biological systems.
It is studied in research models for its involvement in **redox regulation, enzymatic detoxification, and cellular stress response** pathways.
For laboratory research use only — not for human consumption or therapeutic application.

Molecular Characteristics

• Synonyms: GSH; L-Glutathione; γ-L-Glutamyl-L-Cysteinyl-Glycine
• CAS Number: 70-18-8
• Sequence: γ-L-Glutamyl-L-Cysteinyl-Glycine
• Molecular Formula: C₁₀H₁₇N₃O₆S
• Molecular Weight: ≈ 307.3 g/mol
• Purity: ≥ 98% (HPLC verified)
• Formulation: Lyophilized peptide powder

Physical Properties

• Appearance: White to off-white crystalline or lyophilized powder
• Solubility: Sterile water or PBS (for research use only)
• Container: Sterile sealed vial

Storage & Stability

• Unreconstituted: Store at −20 °C, protected from light and moisture.
• Reconstituted: Aliquot and store at −20 °C; avoid repeated freeze–thaw cycles.

Research Context

Glutathione plays a fundamental role in oxidation–reduction balance, detoxification, and enzymatic cofactor studies in biochemical research.
It is used in in vitro and in vivo models investigating **reactive oxygen species (ROS) modulation**, **thiol-based signaling**, and **phase II enzyme pathways**.
Research focuses on its interactions with enzymes such as **glutathione peroxidase, glutathione reductase**, and **glutathione S-transferase** for understanding **antioxidant defense systems** at the molecular level.