HGH Fragment 176–191 — Synthetic Growth Hormone Peptide Research Compound

Catalog ID: HGHF | CAS: 221231-10-3 | Sequence: Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Gly-Ser-Cys-Gly-Phe

Compound Overview

HGH Fragment 176–191 is a synthetic peptide analog representing amino acid residues 176 to 191 of the native human growth hormone sequence.
It is designed for use in research exploring **growth hormone receptor (GHR) signaling**, **metabolic peptide pathways**, and **energy regulation** at the cellular level.
For laboratory research use only — not for human consumption or therapeutic application.

Molecular Characteristics

• Synonyms: HGH Frag 176–191; Somatotropin Fragment; C-terminal GH peptide
• CAS Number: 221231-10-3
• Sequence: Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Gly-Ser-Cys-Gly-Phe
• Molecular Formula: C₇₈H₁₂₃N₂₃O₂₃S₂
• Molecular Weight: ≈ 1817.1 g/mol
• Purity: ≥ 98% (HPLC verified)
• Formulation: Lyophilized peptide powder

Physical Properties

• Appearance: White to off-white lyophilized powder
• Solubility: Sterile water or 0.6% acetic acid (for research use only)
• Container: Sterile sealed vial

Storage & Stability

• Unreconstituted: Store at −20 °C, protected from light and moisture.
• Reconstituted: Aliquot and store at −20 °C; avoid repeated freeze–thaw cycles.

Research Context

HGH Fragment 176–191 is utilized in controlled in vitro and in vivo studies investigating **GH receptor domains**, **metabolic peptide regulation**, and **post-receptor signal transduction**.
Its amino acid sequence corresponds to the C-terminal region of the full 191AA growth hormone molecule, allowing researchers to study **receptor interaction and structural behavior** independent of full-length GH activity.
Research focuses include **AMP-activated protein kinase (AMPK) pathways**, **lipid metabolism models**, and **peptide-driven energy signaling mechanisms**.