TA-1 — Thymosin Alpha-1 Peptide Research Compound

Catalog ID: TA1 | CAS: 14636-12-5 | Sequence: Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn-OH

Compound Overview

Thymosin Alpha-1 (TA-1) is a synthetic thymic peptide consisting of 28 amino acids.
It is supplied in high-purity research-grade form for the investigation of T-cell activation, immune modulation, and intracellular signaling pathways in in vitro and in vivo laboratory models.
Not for human consumption or therapeutic use.

Molecular Characteristics

• Synonyms: Thymosin Fraction 5 Peptide; Tα1
• Sequence: Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn-OH
• Molecular Formula: C₁₂₉H₂₁₅N₃₃O₅₅
• Molecular Weight: ≈ 3108.3 g/mol
• Purity: ≥ 98 % (HPLC)
• Formulation: Lyophilized peptide powder

Physical Properties

• Appearance: White to off-white powder
• Solubility: Sterile water or 0.6 % acetic acid (research use only)
• Container: Sterile sealed vial

Storage & Stability

• Unreconstituted: Store at −20 °C protected from light and moisture.
• Reconstituted: Aliquot and store at −20 °C; avoid repeated freeze–thaw cycles.

Research Context

TA-1 is investigated in laboratory systems to study innate and adaptive immune signaling, cytokine balance, and thymic peptide-mediated gene expression.
It has been widely utilized as a reference peptide in in vitro immunology and peptide receptor research models.