ARA 290 — Synthetic Peptide Research Compound

Catalog ID: ARA2 | CAS: 1206125-18-9 | Sequence: QLQLQK EAENIT ERA TTV

Compound Overview

ARA 290 (also known as pyroglutamate-EPO-derived peptide) is a synthetic 11-amino-acid research peptide modeled on the tertiary loop of human erythropoietin.
It is designed for preclinical evaluation of IRR signaling, microglial modulation, and tissue repair mechanisms under controlled laboratory conditions.
Not for human consumption or therapeutic application.

Molecular Characteristics

• Synonyms: Cibinetide; EPO-Derived Helix B Surface Peptide (HBSP)
• Sequence: QLQLQK EAENIT ERA TTV
• Molecular Formula: C₇₅H₁₂₂N₂₂O₂₅
• Molecular Weight: ≈ 1630 g/mol
• Purity: ≥ 98 % (HPLC)
• Formulation: Lyophilized powder

Physical Properties

• Appearance: White to off-white lyophilized powder
• Solubility: Sterile water or 0.6 % acetic acid (research use only)
• Container: Sterile glass vial

Storage & Stability

• Unreconstituted: Store at −20 °C, protected from light and moisture.
• Reconstituted: Aliquot and store at −20 °C; avoid repeated freeze–thaw cycles.

Research Context

Laboratory studies employing ARA 290 investigate its interaction with the CD131/EPOR innate repair receptor complex,
focusing on erythropoietin-independent signal transduction, cytokine balance, and cellular resilience.
Research applications include examining neuroinflammatory response, microvascular integrity, and metabolic recovery in model systems.