GHRP-6 — Growth Hormone Releasing Hexapeptide Research Compound

Catalog ID: GHR6 | CAS: 87616-84-0 | Sequence: His-D-Trp-Ala-Trp-D-Phe-Lys-NH₂

Compound Overview

GHRP-6 (Growth Hormone Releasing Peptide-6) is a synthetic hexapeptide that binds to the **growth hormone secretagogue receptor (GHSR)**, a member of the **ghrelin receptor family**.
It is utilized in biochemical and physiological research models investigating pituitary cell signaling, G-protein receptor activation, and peptide-induced growth hormone regulation.
For laboratory research use only — not for human consumption or therapeutic application.

Molecular Characteristics

• Synonyms: Growth Hormone Releasing Peptide-6; GHRP6; His-D-Trp-Ala-Trp-D-Phe-Lys-NH₂
• CAS Number: 87616-84-0
• Sequence: His-D-Trp-Ala-Trp-D-Phe-Lys-NH₂
• Molecular Formula: C₄₆H₅₆N₁₂O₆
• Molecular Weight: ≈ 873.0 g/mol
• Purity: ≥ 98% (HPLC verified)
• Formulation: Lyophilized peptide powder

Physical Properties

• Appearance: White to off-white lyophilized powder
• Solubility: Sterile water or 0.6% acetic acid (for research use only)
• Container: Sterile sealed vial

Storage & Stability

• Unreconstituted: Store at −20 °C, protected from light and moisture.
• Reconstituted: Aliquot and store at −20 °C; avoid repeated freeze–thaw cycles.

Research Context

GHRP-6 is used in in vitro and in vivo studies to explore **growth hormone release mechanisms**, **ghrelin receptor signaling**, and **neuroendocrine feedback loops**.
Research emphasizes its role in **pituitary gland peptide responses**, **cyclic AMP (cAMP) modulation**, and **GPCR-based receptor affinity mapping**.
It is frequently compared with related analogs such as **GHRP-2**, **Ipamorelin**, and **Hexarelin** for receptor specificity and binding kinetics research.