Ipamorelin — GH Secretagogue Research Compound

Catalog ID: IPAM | CAS: 170851-70-4 | Sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH₂

Compound Overview

Ipamorelin is a synthetic growth hormone secretagogue (GHS) composed of five amino acids that selectively activate the GHS receptor (GHSR-1a).
It is utilized in in vitro and in vivo research to investigate pituitary signal transduction, peptide selectivity, and somatotropic response pathways.
For laboratory research use only — not for human consumption or therapeutic use.

Molecular Characteristics

• Synonyms: Ipamorelin acetate; Growth hormone secretagogue analog
• CAS Number: 170851-70-4
• Sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH₂
• Molecular Formula: C₃₈H₄₉N₉O₅
• Molecular Weight: ≈ 711.9 g/mol
• Purity: ≥ 98% (HPLC verified)
• Formulation: Lyophilized peptide powder

Physical Properties

• Appearance: White to off-white lyophilized powder
• Solubility: Sterile water or 0.6 % acetic acid (for laboratory use only)
• Container: Sterile sealed vial

Storage & Stability

• Unreconstituted: Store at −20 °C, protected from light and moisture.
• Reconstituted: Aliquot and store at −20 °C; avoid repeated freeze–thaw cycles.

Research Context

Ipamorelin is used in laboratory studies to explore GHSR-1a receptor activation, cAMP-mediated signaling, and peptide selectivity within the somatotropic axis.
Comparative research evaluates its binding profile relative to other secretagogues such as GHRP-2 and GHRP-6, offering insights into pituitary regulation and downstream peptide cascades.
Studies emphasize its use as a tool compound for understanding selective growth hormone release mechanisms.