GHK-Cu — Copper Tripeptide-1 Research Compound

Catalog ID: GHKC | CAS: 49557-75-7 | Sequence: Gly-His-Lys-Cu

Compound Overview

GHK-Cu (Copper Tripeptide-1) is a naturally occurring tripeptide complexed with copper (II) ions.
It is studied in laboratory research for its influence on cellular communication, gene expression regulation, and metalloprotein activity.
This compound serves as a key model for investigating **metal-peptide coordination chemistry** and **cell-matrix interaction dynamics**.
For laboratory research use only — not for human consumption or therapeutic application.

Molecular Characteristics

• Synonyms: Copper Tripeptide-1; GHK-Cu complex
• CAS Number: 49557-75-7
• Sequence: Gly-His-Lys-Cu
• Molecular Formula: C₁₄H₂₄N₆O₄Cu
• Molecular Weight: ≈ 403.9 g/mol
• Purity: ≥ 98% (HPLC verified)
• Formulation: Lyophilized peptide powder

Physical Properties

• Appearance: Blue to blue-green lyophilized powder
• Solubility: Sterile water or dilute acetic acid (for research use only)
• Container: Sterile sealed vial

Storage & Stability

• Unreconstituted: Store at −20 °C, protected from light and moisture.
• Reconstituted: Aliquot and store at −20 °C; avoid repeated freeze–thaw cycles.

Research Context

GHK-Cu is utilized in biochemical research examining metal–peptide coordination, tissue remodeling, and cellular stress response signaling.
Its high affinity for copper ions enables studies of **redox balance**, **gene transcription modulation**, and **collagen-related matrix activity**.
Research emphasizes its role as a metallopeptide regulator in in vitro and in vivo models exploring **oxidative defense and peptide–metal homeostasis**.